Magnetic
nanoparticles were creatively selected as stable, inexpensive,
biodegradable, facile recoverable, and functionalizable supports for a
variety of synthetic and natural polymers. Herein, for the first time,
aromatic polyamide was synthesized on the magnetic core of zinc iron
oxide (ZnFe2O4). Terephthaloyl chloride and
derivations of phenylenediamine were employed as monomers in this
polymerization process. The toxicity of the synthesized hybrid at the
highest concentration (1000 μg/ml) is 13.65% and on the other hand, the
cell viability percentage is 86.35%. So, the prepared hybrid is
biocompatible and non-toxic to Hu02 cells. Also, it has antibacterial
ability against gram-positive and gram-negative bacteria. Because the
results show that the minimum inhibitory concentration (MIC) of the
synthesized polymer for bacteria such as Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, and Pseudomonas aeruginosa ATCC 27853 is in the range of 500–1000 µg/ml. Moreover, the hemolytic effect of ZnFe2O4 based hybrid was below 9% at the concentration of 1000 μg/ml. Therefore, it is compatible with red blood cells.